6-day-old Male in Medicine / Internal Medicine — Case | Hematology | SMLE Q#17717

SMLE Question #17717

Medicine / Internal Medicine Hematology

Objective: OBJ-COAG-NEO-001

Last updated: February 2026
A 6-day-old male neonate has persistent oozing and intermittent bleeding from the umbilical stump since birth. The cord has not separated. An older brother had a similar neonatal bleeding history. The infant feeds well and has no petechiae or mucosal bleeding. Screening haemostasis tests are shown below. Which coagulation factor deficiency best explains these findings?

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