Positive Lupus Anticoagulant Test in Medicine / Internal Medicine — 20yo Woman | Hematology | SMLE Q#18700

SMLE Question #18700

Medicine / Internal Medicine Hematology

Objective: OBJ-APH-001

Last updated: February 2026
A 20-year-old woman is evaluated for recurrent pregnancy loss. She has had three spontaneous miscarriages before 10 weeks’ gestation. One year ago, she was treated for an unprovoked pulmonary embolism and is not currently taking anticoagulants. Her coagulation profile shows an isolated prolonged aPTT with a positive lupus anticoagulant test. What is the most likely diagnosis?

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