3-month Painless Swelling On in Medicine / Internal Medicine — 22yo Man | Hematology | SMLE Q#17163

SMLE Question #17163

Medicine / Internal Medicine Hematology

Objective: OBJ-101

Last updated: February 2026
A 22-year-old man presents with a 3-month history of painless swelling on the left side of his neck. He has drenching night sweats and an unintentional 5 kg weight loss over 2 months. He denies recent upper respiratory infection, dental infection, or travel. Examination shows several firm, rubbery, non-tender left cervical lymph nodes, the largest 2.5 cm, with no skin changes. No hepatosplenomegaly is detected. What is the most likely diagnosis?

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