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SMLE Question #16859

Medicine / Internal Medicine Hematology

Objective: OBJ-101

Last updated: February 2026
A 41-year-old man receives packed red blood cells for postoperative bleeding on the surgical ward. Within minutes of starting the transfusion, he develops severe pain along the infusion vein, fever, and chest tightness. The transfusion is stopped immediately, and the IV line is kept open with 0.9% saline. Which of the following is the most likely diagnosis?

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