Otherwise Stable Results in Medicine / Internal Medicine — 64yo Man | Hematology | SMLE Q#12324

SMLE Question #12324

Medicine / Internal Medicine Hematology

Objective: OBJ-101

Last updated: February 2026
A 64-year-old man is hospitalized for acute proximal deep vein thrombosis and has been receiving an intravenous unfractionated heparin infusion for 3 days. He has no bleeding, bruising, or new symptoms. Routine monitoring shows a markedly prolonged activated partial thromboplastin time with otherwise stable results. What is the most appropriate next step in management of his anticoagulation?

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