Long-standing Rheumatoid Arthritis Treated in Medicine / Internal Medicine — 59yo Woman | Hematology | SMLE Q#11159

SMLE Question #11159

Medicine / Internal Medicine Hematology

Objective: OBJ-101

Last updated: February 2026
A 59-year-old woman with long-standing rheumatoid arthritis treated with methotrexate reports 3 months of progressive fatigue, intermittent headaches, and dyspnea on exertion. Examination shows pale conjunctiva and swollen, tender metacarpophalangeal joints. What is the most likely cause of this patient’s anemia?

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