Newly Diagnosed Burkitt Lymphoma in Medicine / Internal Medicine — 9yo Child | Oncology | SMLE Q#876

SMLE Question #876

Medicine / Internal Medicine Oncology
Last updated: February 2026
A 9-year-old boy with newly diagnosed Burkitt lymphoma starts intensive induction chemotherapy. Within 24 hours, he develops nausea, vomiting, oliguria, and lethargy. He has no prior kidney disease. Initial evaluation shows acute kidney injury with metabolic acidosis and elevated uric acid and phosphate, consistent with tumor lysis physiology. Which electrolyte pattern is most characteristic of tumor lysis syndrome?

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