Helicobacter Pylori in Medicine / Internal Medicine — 56yo Man | Oncology | SMLE Q#8196

SMLE Question #8196

Medicine / Internal Medicine Oncology

Objective: OBJ-191

Last updated: February 2026
A 56-year-old man has 3 months of progressive epigastric pain, early satiety, bloating, and an unintentional 6 kg weight loss. Upper endoscopy shows an irregular antral mass, and biopsy confirms gastric mucosa-associated lymphoid tissue (MALT) lymphoma. A urea breath test is positive for Helicobacter pylori. Staging imaging shows no regional lymphadenopathy or distant disease. Which of the following is the next best step in management?

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