45-year-old Woman in Medicine / Internal Medicine — 45yo Woman | Oncology | SMLE Q#750
SMLE Question #750
Medicine / Internal Medicine
Oncology
Last updated: February 2026
A 45-year-old woman has 3 months of progressive fatigue, unintentional 4-kg weight loss, and night sweats. She denies recent travel or sick contacts. Examination shows non-tender, rubbery cervical and axillary lymphadenopathy without hepatosplenomegaly. A chest radiograph shows mediastinal widening. Initial blood work shows normocytic anemia and elevated lactate dehydrogenase. Which of the following is the most appropriate next step in management?
Continue in practice mode
Sign in and start a focused practice session to view options, submit your answer, and read the full explanation.