Widely Spaced Nipples in Pediatrics — 15yo Child | Pediatric Endocrinology | SMLE Q#740

SMLE Question #740

Pediatrics Pediatric Endocrinology
Last updated: February 2026
A 15-year-old girl is evaluated for short stature and delayed puberty. She has not had menarche. Height is at the 3rd percentile and weight at the 25th percentile. Examination shows a webbed neck, broad chest with widely spaced nipples, and a low posterior hairline. Cardiac examination reveals a systolic murmur. Pelvic ultrasonography shows streak gonads and a small uterus. Karyotype analysis is ordered. Which karyotype is most consistent with her condition?

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