Ambiguous Genitalia Is Admitted in Pediatrics — Case | Pediatric Endocrinology | SMLE Q#11777
SMLE Question #11777
Pediatrics
Pediatric Endocrinology
Objective: OBJ-173
Last updated: February 2026
A 24-hour-old term newborn with ambiguous genitalia is admitted for poor feeding and repeated vomiting. Exam shows clitoromegaly, partial labioscrotal fusion, and a single urogenital opening; no palpable gonads. The infant is lethargic and clinically dehydrated. Initial blood tests show hyponatraemia, hyperkalaemia, metabolic acidosis, and hypoglycaemia; serum 17-hydroxyprogesterone is elevated. What is the most appropriate immediate management?
Continue in practice mode
Sign in and start a focused practice session to view options, submit your answer, and read the full explanation.