Baby in Medicine / Internal Medicine — Case | Psychiatry | SMLE Q#16695

SMLE Question #16695

Medicine / Internal Medicine Psychiatry

Objective: OBJ-253

Last updated: February 2026
A 24-year-old primiparous woman presents to a family medicine clinic 5 weeks after an uncomplicated vaginal delivery. For the past 3 weeks, she has had persistent low mood and tearfulness, loss of interest, reduced appetite, and insomnia despite the newborn sleeping. She feels excessive guilt and reports reduced bonding with the baby, requiring significant help from her partner for daily tasks. She denies suicidal thoughts, thoughts of harming the baby, hallucinations, delusions, or periods of abnormally elevated mood. Physical examination is unremarkable. What is the most likely diagnosis?

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