Alzheimer Disease Is Brought in Medicine / Internal Medicine — 82yo Woman | Psychiatry | SMLE Q#1488
SMLE Question #1488
Medicine / Internal Medicine
Psychiatry
Last updated: February 2026
An 82-year-old woman with Alzheimer disease is brought from a nursing facility for 2 days of severe agitation and physical aggression (pacing, shouting, attempting to strike staff). There have been no recent medication changes. Nonpharmacologic measures (reorientation, calm environment, familiar caregivers) have not improved symptoms. Assessment has not identified an acute medical cause. Between episodes, she does not report hallucinations or fixed delusions. Which medication is most appropriate to control her acute agitation?
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