1 Day Of Severe in Medicine / Internal Medicine — 24yo Woman | Psychiatry | SMLE Q#1455

SMLE Question #1455

Medicine / Internal Medicine Psychiatry
Last updated: February 2026
A 24-year-old woman, 2 weeks after an uncomplicated vaginal delivery, is brought to the emergency department for 1 day of severe confusion and disorientation. She gives inappropriate answers, has slept only 1–2 hours nightly, appears fearful, and intermittently responds to unseen stimuli. She states her newborn is “lucky to be alive” and “will not live long” despite reassurance the infant is healthy. She has no previous psychiatric history or substance use. What is the most likely diagnosis?

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