28-year-old Woman in Medicine / Internal Medicine — 28yo Woman | Psychiatry | SMLE Q#1426
SMLE Question #1426
Medicine / Internal Medicine
Psychiatry
Last updated: February 2026
A 28-year-old woman has had 2 months of persistent low mood, loss of interest, low energy, and poor concentration causing impairment at work. She denies substance use and has no history of manic or hypomanic symptoms. Mental status examination shows depressed affect without thought disorder. Which of the following is a DSM-5 diagnostic symptom of a major depressive episode?
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