3 Months Of Low in Medicine / Internal Medicine — 34yo Woman | Psychiatry | SMLE Q#1414
SMLE Question #1414
Medicine / Internal Medicine
Psychiatry
Last updated: February 2026
A 34-year-old woman presents to an outpatient psychiatry clinic with 3 months of low mood, anhedonia, fatigue, and poor concentration and is diagnosed with major depressive disorder. She has no history of mania or hypomania, psychosis, or substance use, and she denies suicidal ideation. Physical examination and basic laboratory tests are unremarkable. She is started on an SSRI. What is the most appropriate next step in management after initiating SSRI therapy?
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