6 Weeks Of Low in Medicine / Internal Medicine — Case | Psychiatry | SMLE Q#12164
SMLE Question #12164
Medicine / Internal Medicine
Psychiatry
Objective: OBJ-253
Last updated: February 2026
A 22-year-old university student presents to a primary care clinic with 6 weeks of low mood, impaired concentration, reduced energy, insomnia, and 3-kg unintentional weight loss. She reports diminished enjoyment in daily activities. She has no history of bipolar disorder or substance use, and she denies current thoughts of self-harm when asked. You are assessing symptom features that indicate higher immediate safety risk in depressive disorders. Which of the following symptoms is most concerning and requires the most urgent assessment?
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