>50 Pack-year Smoking History in Medicine / Internal Medicine — 70yo Man | Oncology | SMLE Q#11463

SMLE Question #11463

Medicine / Internal Medicine Oncology

Objective: OBJ-191

Last updated: February 2026
A 70-year-old man with >50 pack-year smoking history has 5 months of progressive dyspnoea and productive cough. He reports malaise, drenching night sweats, and unintentional 10 kg weight loss over 3 months. Examination shows a thin, fatigued man with digital clubbing and reduced breath sounds with focal crackles over the right upper zone. What is the most likely diagnosis?

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