52-year-old Man in Surgery — 52yo Man | Orthopedics | SMLE Q#9473

SMLE Question #9473

Surgery Orthopedics

Objective: OBJ-316

Last updated: February 2026
A 52-year-old man has a 3-month history of a gradually enlarging, firm, mildly tender mass in the anterolateral right thigh. MRI shows a 9-cm deep intramuscular mass within the quadriceps abutting the femur. CT chest/abdomen/pelvis shows no metastases. The team is planning definitive limb-sparing surgery if malignancy is confirmed. Which of the following is the most appropriate biopsy technique to establish the diagnosis?

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