1 Day Of Dysuria in Medicine / Internal Medicine — Case | Infectious Diseases | SMLE Q#825

SMLE Question #825

Medicine / Internal Medicine Infectious Diseases
Last updated: February 2026
A 26-year-old nonpregnant woman presents with 1 day of dysuria, urinary frequency, right flank pain, fever, and chills. She is alert and not toxic-appearing. Examination shows right costovertebral angle tenderness; abdomen is benign. Urinalysis shows pyuria and positive leukocyte esterase with a few red blood cells; urine culture is pending. She has no comorbidities and takes no regular medications. What is the most appropriate initial management?

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