Acute Myeloid Leukemia Is in Medicine / Internal Medicine — 54yo Man | Infectious Diseases | SMLE Q#12546

SMLE Question #12546

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 54-year-old man with acute myeloid leukemia is admitted for induction chemotherapy. On day 8, he develops sudden chills and feels unwell. He has no localizing symptoms, and the central venous catheter site appears clean. Blood and urine cultures are obtained. What is the most appropriate immediate management?

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