Hypertension in Medicine / Internal Medicine — 54yo Man | Neurology | SMLE Q#3845

SMLE Question #3845

Medicine / Internal Medicine Neurology
Last updated: February 2026
A 54-year-old man with hypertension and hyperlipidaemia develops sudden right arm and leg weakness and slurred speech at work 45 minutes ago. He is awake with right facial droop and difficulty producing speech. Examination shows right hemiparesis with increased tone and hyperreflexia. Non-contrast CT brain shows no acute intracranial haemorrhage. Which pathophysiologic mechanism most likely explains his neurologic deficits?

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