High Transmission Of Chloroquine-resistant in Medicine / Internal Medicine — Case | Infectious Diseases | SMLE Q#344

SMLE Question #344

Medicine / Internal Medicine Infectious Diseases
Last updated: February 2026
A 27-year-old Saudi male soldier will deploy for 6 weeks to a rural forested area in sub-Saharan Africa with high transmission of chloroquine-resistant Plasmodium falciparum. He has no chronic illnesses, takes no regular medications, and has no known G6PD deficiency. Physical examination and baseline screening tests are unremarkable. Which medication is the most appropriate malaria chemoprophylaxis for this mission?

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