Alzheimer Disease in Medicine / Internal Medicine — 72yo Man | Neurology | SMLE Q#18828
SMLE Question #18828
Medicine / Internal Medicine
Neurology
Objective: OBJ-305
Last updated: March 2026
A 72-year-old man has 2 years of progressive short-term memory loss and difficulty managing finances. He was diagnosed with Alzheimer disease and has taken donepezil 10 mg daily for 6 months with good adherence and no adverse effects. His family reports continued cognitive and functional decline. He has no prominent depressed mood, hallucinations, or parkinsonism. Montreal Cognitive Assessment score is 16/30. Brain MRI shows diffuse cortical atrophy without focal lesions. What is the most appropriate medication adjustment?
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