Sickle Cell Disease Is in Medicine / Internal Medicine — 22yo Man | Infectious Diseases | SMLE Q#18598
SMLE Question #18598
Medicine / Internal Medicine
Infectious Diseases
Objective: OBJ-001
Last updated: February 2026
A 22-year-old man with sickle cell disease is day 4 after an allogeneic hematopoietic stem cell transplant. He developed fever and chills and was started on IV ceftazidime. After 72 hours, he remains febrile with no clinical improvement; blood cultures to date show no growth. He has a tunneled central venous catheter with mild erythema at the insertion site and no purulence. What is the most appropriate antibiotic to add to his regimen?
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