Chronic Hepatitis B (hbsag in Medicine / Internal Medicine — 43yo Man | Hepatology | SMLE Q#18593
SMLE Question #18593
Medicine / Internal Medicine
Hepatology
Objective: OBJ-HEP-HBV-001
Last updated: February 2026
A 43-year-old man with chronic hepatitis B (HBsAg positive for >6 months) attends a routine follow-up. He is asymptomatic, and physical examination is unremarkable. Over the past 6 months, his aminotransferases have remained elevated, and HBV DNA has been persistently high. Abdominal ultrasound shows mildly coarse liver echotexture. He has a history of major depressive disorder. What is the most appropriate treatment option?
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