No Clinical Features Of in Medicine / Internal Medicine — 45yo Man | Hepatology | SMLE Q#16385

SMLE Question #16385

Medicine / Internal Medicine Hepatology

Objective: OBJ-HEP-01

Last updated: February 2026
A 45-year-old man is evaluated in a hepatology clinic after a new diagnosis of chronic hepatitis C infection. He is asymptomatic, denies alcohol use, and has never received antiviral therapy. Complete blood count and serum creatinine are normal. Abdominal ultrasound shows no cirrhosis or focal lesions. Transient elastography suggests advanced fibrosis (F3) with no clinical features of decompensated liver disease. Which of the following is the most appropriate recommended treatment for this patient?

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