Chills in Medicine / Internal Medicine — 28yo Man | Infectious Diseases | SMLE Q#18467

SMLE Question #18467

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-001

Last updated: February 2026
A 28-year-old man returns to Saudi Arabia after 3 weeks in sub-Saharan Africa. For 5 days, he has had intermittent fever with chills, headache, and myalgias. He did not take malaria chemoprophylaxis. He is alert, able to tolerate oral intake, and has no jaundice, bleeding, or respiratory distress. Thick and thin blood films identify Plasmodium falciparum. What is the most appropriate treatment?

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