Reduced Urine Volume in Pediatrics — 9yo Child | Pediatric Endocrinology | SMLE Q#18255

SMLE Question #18255

Pediatrics Pediatric Endocrinology

Objective: OBJ-173

Last updated: February 2026
A 9-year-old boy has several months of polyuria, polydipsia, and new-onset nocturia. He drinks water frequently and wakes 3–4 times nightly to urinate. Examination is unremarkable and he appears well hydrated. A supervised water-deprivation test is performed. After dehydration, urine osmolality changes minimally; after administration of a synthetic antidiuretic hormone analogue, urine osmolality increases markedly with reduced urine volume. What is the most appropriate long-term management?

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