24 Hours Of Worsening in Medicine / Internal Medicine — 32yo Woman | Neurology | SMLE Q#18146

SMLE Question #18146

Medicine / Internal Medicine Neurology

Objective: OBJ-NEURO-OPTICNEURITIS-01

Last updated: February 2026
A 32-year-old woman presents to the Emergency Department with 24 hours of worsening right-eye vision loss and pain with eye movement. She reports reduced colour saturation. Examination shows decreased visual acuity in the right eye and a right relative afferent pupillary defect; fundoscopy is unremarkable. MRI brain/orbits with gadolinium shows enhancement of the right optic nerve with periventricular ovoid white-matter lesions. What is the most appropriate initial management?

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