Alzheimer Disease Has Taken in Medicine / Internal Medicine — 74yo Man | Neurology | SMLE Q#18125

SMLE Question #18125

Medicine / Internal Medicine Neurology

Objective: OBJ-NEURO-AD-001

Last updated: February 2026
A 74-year-old man with Alzheimer disease has taken donepezil 10 mg daily for 8 months with good adherence. Over 4 months, his spouse notes worsening short-term memory and difficulty managing finances. Mini-Mental State Examination declined from 20/30 to 16/30. He has no hallucinations, major depressive symptoms, or intercurrent acute illness. What is the most appropriate medication adjustment?

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