Acute Left-sided Pyelonephritis in Medicine / Internal Medicine — 48yo Woman | Infectious Diseases | SMLE Q#17945

SMLE Question #17945

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 48-year-old woman is hospitalized for acute left-sided pyelonephritis and has received IV ceftriaxone for 5 days. She has persistent fever and worsening left flank pain. She has no indwelling urinary catheter and no prior nephrolithiasis. Examination shows left costovertebral angle tenderness without peritonitis. What is the most appropriate next step in management?

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