Community-acquired Pneumonia in Medicine / Internal Medicine — 52yo Man | Infectious Diseases | SMLE Q#17651

SMLE Question #17651

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-IM-ID-DRUGAE-THROMBO

Last updated: February 2026
A 52-year-old man is admitted with community-acquired pneumonia. He is started on IV antibiotics and an oral macrolide, and receives analgesia for pleuritic pain. After 24 hours, his fever and cough improve, but oxygenation remains low. He has new isolated thrombocytopenia with no previous history of low platelets. He has no mucosal bleeding, petechiae, or hepatosplenomegaly. Which medication should be stopped as the most likely cause of the new thrombocytopenia?

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