Rheumatic Heart Disease in Medicine / Internal Medicine — 38yo Woman | Infectious Diseases | SMLE Q#16581

SMLE Question #16581

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 38-year-old woman has a mechanical mitral valve placed 10 years ago for rheumatic heart disease and takes long-term warfarin. She has no history of infective endocarditis and no drug allergies. She is scheduled for a dental extraction that involves manipulation of gingival tissue. Which antibiotic prophylaxis regimen is most appropriate to prevent infective endocarditis in this patient?

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