Isoniazid in Medicine / Internal Medicine — 72yo Man | Infectious Diseases | SMLE Q#1618

SMLE Question #1618

Medicine / Internal Medicine Infectious Diseases
Last updated: February 2026
A 72-year-old man has 3 months of cough, intermittent low-grade fever, night sweats, and 5-kg unintentional weight loss. Chest X-ray shows a right upper lobe cavitary infiltrate. Sputum smear is positive for acid-fast bacilli. Standard first-line therapy with isoniazid, rifampicin, pyrazinamide, and ethambutol is planned. Which initial baseline test should be obtained before starting this treatment course?

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