38-year-old Woman in Medicine / Internal Medicine — 38yo Woman | Infectious Diseases | SMLE Q#12412

SMLE Question #12412

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 38-year-old woman attends an outpatient visit 8 weeks after an uncomplicated term vaginal delivery. She is exclusively breastfeeding. She reports no dysuria, frequency, urgency, suprapubic pain, flank pain, fever, or chills. Physical examination is unremarkable. A midstream urine culture sent at this visit grows Escherichia coli. Which of the following is the most appropriate next step in management?

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