Multiple Closed Long-bone Fractures in Medicine / Internal Medicine — 24yo Man | Infectious Diseases | SMLE Q#12317
SMLE Question #12317
Medicine / Internal Medicine
Infectious Diseases
Objective: OBJ-349
Last updated: February 2026
A 24-year-old man is admitted after a high-speed motor vehicle collision with multiple closed long-bone fractures. After initial resuscitation, he is stable and is planned for operative fixation. He has no history of immunosuppression, is not receiving total parenteral nutrition, and has no indwelling central venous catheter. He has no local wound contamination and no clinical features suggesting systemic infection. The team asks whether empiric systemic antifungal therapy should be added to routine perioperative antibacterial prophylaxis. What is the most appropriate management regarding antifungal therapy?
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