Newly Diagnosed Pulmonary Tuberculosis in Medicine / Internal Medicine — 46yo Man | Infectious Diseases | SMLE Q#12293
SMLE Question #12293
Medicine / Internal Medicine
Infectious Diseases
Objective: OBJ-349
Last updated: February 2026
A 46-year-old man with newly diagnosed pulmonary tuberculosis starts standard 4-drug therapy. Two weeks later, he develops nausea, poor appetite, and right upper quadrant discomfort. He does not drink alcohol. Examination shows mild right upper quadrant tenderness without jaundice. Investigations show a marked hepatocellular pattern of liver injury. Which first-line antitubercular drug is most likely responsible?
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