2 Weeks Of Fever in Medicine / Internal Medicine — 32yo Man | Infectious Diseases | SMLE Q#12224

SMLE Question #12224

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 32-year-old man presents with 2 weeks of fever, severe headache, photophobia, and progressive neck stiffness. He reports unintentional weight loss and night sweats. Examination shows meningism with positive Kernig and Brudzinski signs. Lumbar puncture is performed; CSF Gram stain is negative and bacterial culture is pending. What is the most likely diagnosis?

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