Homozygous Sickle Cell Disease in Medicine / Internal Medicine — 19yo Man | Infectious Diseases | SMLE Q#11555
SMLE Question #11555
Medicine / Internal Medicine
Infectious Diseases
Objective: OBJ-349
Last updated: February 2026
A 19-year-old man with homozygous sickle cell disease is 10 days after an allogeneic hematopoietic stem cell transplant. He has 6 hours of fever and chills. Examination shows no focal infection; the central venous catheter site is clean without erythema or tenderness. Blood cultures are obtained. Which empiric antimicrobial therapy is most appropriate initially?
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