5 Days Of Fever in Medicine / Internal Medicine — 35yo Man | Infectious Diseases | SMLE Q#11535
SMLE Question #11535
Medicine / Internal Medicine
Infectious Diseases
Objective: OBJ-349
Last updated: February 2026
A 35-year-old man who recently immigrated from India presents with 5 days of fever, severe headache, progressive fatigue, and neck stiffness. He reports night sweats and unintentional 4-kg weight loss over 2 months. Examination shows meningeal signs. CT brain shows no mass effect or hydrocephalus. Cerebrospinal fluid obtained by lumbar puncture forms a delicate clot on standing. What is the most likely diagnosis?
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