Non-hodgkin Lymphoma 7 Days in Medicine / Internal Medicine — 17yo Child | Infectious Diseases | SMLE Q#11466
SMLE Question #11466
Medicine / Internal Medicine
Infectious Diseases
Objective: OBJ-349
Last updated: February 2026
A 17-year-old boy with non-Hodgkin lymphoma presents 7 days after chemotherapy with fever, rigors, and confusion. Examination shows no focal source of infection; the implanted port site has no erythema or discharge. Despite 30 mL/kg IV crystalloids, he remains hypotensive and is started on norepinephrine. Blood cultures are obtained before antibiotics. What is the most appropriate initial empiric antimicrobial therapy for febrile neutropenia with septic shock?
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