Drug-susceptible Pulmonary Tuberculosis in Medicine / Internal Medicine — 46yo Man | Infectious Diseases | SMLE Q#11378

SMLE Question #11378

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 46-year-old man is receiving intensive-phase therapy for drug-susceptible pulmonary tuberculosis. He develops sudden severe pain, erythema, and swelling of the right first metatarsophalangeal joint. Arthrocentesis shows needle-shaped, negatively birefringent crystals. He has no prior history of gout. Which anti-tubercular drug in his regimen is most likely responsible for his hyperuricemia?

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