Painful Penile Ulcers in Medicine / Internal Medicine — Case | Infectious Diseases | SMLE Q#11111

SMLE Question #11111

Medicine / Internal Medicine Infectious Diseases

Objective: OBJ-349

Last updated: February 2026
A 28-year-old sexually active man presents with painful penile ulcers for 5 days after unprotected intercourse with a new partner 1 week ago. Examination shows multiple shallow ulcers with ragged, undermined edges and a yellow-gray necrotic base. He has markedly tender inguinal lymphadenopathy. What is the most likely diagnosis?

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