Rapidly Enlarging Anterior Neck in Medicine / Internal Medicine — 52yo Woman | Endocrinology | SMLE Q#9731
SMLE Question #9731
Medicine / Internal Medicine
Endocrinology
Objective: OBJ-ADDISON-DOSE-1
Last updated: February 2026
A 52-year-old woman presents with a rapidly enlarging anterior neck swelling for 4 weeks. She has lost 6 kg unintentionally and reports mild dysphagia without dyspnea or hoarseness. She has a 25-year history of Hashimoto thyroiditis treated with stable levothyroxine. Examination shows a firm, non-tender, asymmetrically enlarged thyroid mass with poorly defined margins and minimal cervical lymphadenopathy. There is no recent trauma and no anticoagulant use. What is the most likely diagnosis?
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