No Nipple Discharge Or in Surgery — 43yo Woman | General Surgery | SMLE Q#942

SMLE Question #942

Surgery General Surgery

Objective: OBJ-TRACH-EMERG-01

Last updated: February 2026
A 43-year-old woman is referred after a screening mammogram detected a well-circumscribed left breast mass. She noticed a rapidly enlarging, painless lump for 4 months with no nipple discharge or weight loss. Ultrasound shows a solid 5.5-cm lesion in the upper outer quadrant with no abnormal axillary nodes. Core-needle biopsy shows a fibroepithelial neoplasm with marked stromal overgrowth, nuclear atypia, and increased mitotic activity. No clinical features suggest distant metastasis. What is the most appropriate next step in management?

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