Intervening Normal-appearing Mucosa in Medicine / Internal Medicine — 26yo Man | Gastroenterology | SMLE Q#917
SMLE Question #917
Medicine / Internal Medicine
Gastroenterology
Last updated: February 2026
A 26-year-old man has 6 months of crampy right lower quadrant abdominal pain, non-bloody diarrhoea, and 5-kg unintentional weight loss. He reports intermittent low-grade fever and fatigue. Ileocolonoscopy shows discontinuous segments of inflamed mucosa with intervening normal-appearing mucosa and a cobblestone pattern, with features suggesting transmural inflammation. What is the most common site of involvement in this condition?
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