2 Days Of High in Pediatrics — Case | Pediatric Infectious | SMLE Q#809
SMLE Question #809
Pediatrics
Pediatric Infectious
Objective: OBJ-113
Last updated: February 2026
A 15-month-old boy is brought to the emergency department with 2 days of high fever, vomiting, and irritability. Today, he had a generalized tonic-clonic seizure lasting 2 minutes. He is lethargic with a bulging anterior fontanelle and neck stiffness. Lumbar puncture shows purulent cerebrospinal fluid with elevated opening pressure; Gram stain shows numerous gram-positive cocci in chains. What is the most appropriate empiric intravenous antibiotic regimen?
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