Effortless Regurgitation Of Undigested in Medicine / Internal Medicine — 45yo Man | Gastroenterology | SMLE Q#788

SMLE Question #788

Medicine / Internal Medicine Gastroenterology
Last updated: February 2026
A 45-year-old man has 1 year of gradually progressive dysphagia to solids and liquids with effortless regurgitation of undigested food, worse when lying down at night. He has no weight loss, odynophagia, or caustic ingestion history. Physical examination is unremarkable. The clinician suspects achalasia and wants to confirm the diagnosis by directly assessing esophageal motor function and lower esophageal sphincter relaxation. What is the best diagnostic test to establish the diagnosis?

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