Single-dose Methotrexate Protocol 3 in Obstetrics & Gynecology — Case | General Gynecology | SMLE Q#535
SMLE Question #535
Obstetrics & Gynecology
General Gynecology
Last updated: February 2026
A 28-year-old G1P0 woman had a hemodynamically stable, unruptured tubal ectopic pregnancy treated with a single-dose methotrexate protocol 3 weeks ago. Her serum b2-hCG was 1200 IU/L at diagnosis, 1000 IU/L at 1 week, and 800 IU/L at 2 weeks. She has mild intermittent spotting but no abdominal pain, dizziness, or syncope. What is the most appropriate next step in management?
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